Enzymes to Enable a Biocatalytic Cascade for Small Molecule API.
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Publications
TIDES USA 2025: Oligonucleotide CMC for Sustainable and Scalable Enzymatic siRNA Manufacturing
TIDES USA 2025: Comparative Analysis of Diastereomeric Distribution in siRNA Synthesis: Phosphoramidite Chemistry vs Enzymatic Synthesis
TIDES USA 2025: Machine Learning-Guided Ligation Fragment Design for Efficient siRNA Synthesis
TIDES EU 2024: Process Development for Enzymatic Synthesis of RNAi Therapeutics, November 2024
Improving siRNA Production Efficiency
RNA Leaders Europe Congress 2025: RNA Synthesis using Ligation for Improved Scalability and Reduced Manufacturing Cost
RNA Leaders USA 2024: Enzymatic Approaches for Large-scale siRNA Synthesis
TIDES USA 2024 Workshop Presentation: Enzymatic Oligonucleotide Synthesis - Process Flow and Substance Impurity Profile