Codexis, Inc.

ECO Synthesis™ technology

Enzyme-catalyzed oligonucleotide synthesis for RNAi therapeutics.

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Codexis, Inc.

2-in-1 RT-LAMP DNA Polymerase

Faster isothermal RNA detection with engineered DNA polymerase.

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Codexis, Inc.

Efficient mRNA capping

Achieve exceptional IVT results with Codex® HiCap RNA Polymerase.

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Codexis, Inc.

Orally administered enzyme therapy

Phase 1 candidates partnered with Nestle Health Science: CDX-7108 for treatment of EPI; CDX-6114 for PKU.

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Explore our applications

Pharmaceutical Manufacturing

Pharmaceutical Manufacturing

Highly customized biocatalysts can transform API manufacturing processes by eliminating steps, increasing yield, and reducing solvent usage and waste. Explore novel approaches that benefit the triple bottom line – social, environmental, and financial.

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Pharmaceutical Manufacturing

Highly customized biocatalysts can transform API manufacturing processes by eliminating steps, increasing yield, and reducing solvent usage and waste. Explore novel approaches that benefit the triple bottom line – social, environmental, and financial.

RNA Manufacturing

RNA Manufacturing

When manufacturing mRNA for therapeutic applications, the process ideally delivers high yields and minimizes unwanted byproducts, while being economically sound. Engineered enzymes can overcome the particular obstacles faced in the production of quality mRNA at commercial scale.

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RNA Manufacturing

When manufacturing mRNA for therapeutic applications, the process ideally delivers high yields and minimizes unwanted byproducts, while being economically sound. Engineered enzymes can overcome the particular obstacles faced in the production of quality mRNA at commercial scale.

Oral Enzyme Therapy

Oral Enzyme Therapy

Highly stable and active recombinant oral enzyme therapies can potentially benefit patients. We engineer enzymes that are highly stable to the harsh conditions of the gastrointestinal tract, including the low pH of the stomach and the protease-rich upper intestines.

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Oral Enzyme Therapy

Highly stable and active recombinant oral enzyme therapies can potentially benefit patients. We engineer enzymes that are highly stable to the harsh conditions of the gastrointestinal tract, including the low pH of the stomach and the protease-rich upper intestines.

NGS Library Prep

NGS Library Prep

Many NGS workflows are critically dependent on library preparation. Engineered enzymes play a key role in effective library preparation to lay the groundwork for high quality sequencing results under increasingly diverse and demanding conditions.

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NGS Library Prep

Many NGS workflows are critically dependent on library preparation. Engineered enzymes play a key role in effective library preparation to lay the groundwork for high quality sequencing results under increasingly diverse and demanding conditions.

Nucleic Acid Detection

Nucleic Acid Detection

Nucleic acid detection methods are valuable diagnostic tools which rely on enzymes to amplify a range of starting samples. Engineered enzymes that have been tailored for real-world laboratory and physiological conditions achieve faster time to results under a wider range of challenging conditions.

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Nucleic Acid Detection

Nucleic acid detection methods are valuable diagnostic tools which rely on enzymes to amplify a range of starting samples. Engineered enzymes that have been tailored for real-world laboratory and physiological conditions achieve faster time to results under a wider range of challenging conditions.

Gene Therapy

Gene Therapy

Engineered proteins may offer improved targeting, expression, and potency when administered as gene therapies. Our partnered product candidates with Takeda are for rare lysosomal storage disorders such as Fabry Disease, Pompe Disease, and a blood factor disorder.

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Gene Therapy

Engineered proteins may offer improved targeting, expression, and potency when administered as gene therapies. Our partnered product candidates with Takeda are for rare lysosomal storage disorders such as Fabry Disease, Pompe Disease, and a blood factor disorder.

Everything we do is to improve health.
Of people and the planet.

At Codexis, we strive to innovate sustainable processes and products, and discover and develop effective therapeutics – all to create a brighter future.

These goals are grand but not beyond reach. Together with our business partners and loyal customers, we can make them a reality.

Event Presentation

Webinar: Advancing mRNA Therapeutics with Engineered Enzymes

Held on March 28, 2023, scientists from Codexis and Tune Therapeutics presented how engineered enzymes can overcome common challenges with capping efficiency and dsRNA impurities in IVT manufacturing of mRNA required for vaccines and cell/gene therapeutics.

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There are many steps to a healthier future.

Join us on our journey.