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Start Smart with Enzyme Screening Kits and Panels
Kickstart biocatalysis with off-the-shelf enzymes for faster feasibility and scale-up confidence.
Enzymes Built for Feasibility and Scale
Codexis screening kits provide immediate access to high-performance enzymes engineered for selectivity, stability, and substrate diversity. From early-stage feasibility to scale-up, our kits are designed to accelerate progress with minimal friction.
Choose from expert-curated KRED, ATA, ERED, and other kits — each backed by decades of engineering insight and available in follow-on quantities up to metric tons.
23+ Years
Of enzyme screening and optimization expertise
Follow-on Ready
With 50–100 g in-stock enzyme quantities
Scalable Supply
Up to metric tons available
Diverse Portfolio
Including KRED, ATA, ERED, and more
Designed to Accelerate Your First Step
Explore the benefits of Codexis screening kits.
Get Feasibility Fast
Evaluate enzyme fit quickly with curated kits.
Go Beyond Off-the-Shelf
Access follow-on support and engineering options.
Save Time, Reduce Risk
Fewer dead ends with proven biocatalysts.
Access Expert Guidance
Tap into our biocatalysis and process expertise.
Our Kits, Your Starting Advantage
Each screening kit is built from Codexis’ trusted enzyme toolbox, designed to reveal possibilities early. Whether you’re targeting asymmetric reductions or tricky amide synthesis, our enzymes bring broad substrate compatibility, stability and activity to the table.
Our portfolio of Biocatalysts, Screening Kits and Recycling Enzymes
Transaminases perform the asymmetric conversion of ketones to chiral amines using isopropylamine as an amine donor.
Codex ATA Screening Kit
The Codex ATA Screening Kit contains 24 amine transaminase enzymes for converting ketones into chiral amines. This selected set of engineered enzymes has a broad substrate range, diverse stereoselectivity, improved solvent stability and can operate on a wide range of temperatures and pHs. 100 g of each kit enzyme is available from stock, and larger quantities up to tons are available on demand. The kit contains 24 x 250 mg enzymes and 300mg PLP cofactor.
Ketoreductases perform the asymmetric reduction of carbonyls to alcohols using nicotinamide cofactors as electron donors.
Codex KRED Screening Kit
The Codex KRED Screening Kit contains 24 ketoreductase enzymes for converting ketones into chiral alcohols. This selected set of engineered enzymes has a broad substrate range, diverse stereoselectivity, improved solvent stability and can operate on a wide range of temperatures and pHs. 100 g of each kit enzyme is available from stock, and larger quantities up to tons are available on demand. The kit contains 24 x 250 mg enzymes and a KRED reaction buffer mix.
Our Esterases are capable of amide synthesis using corresponding ester and amine substrates, as well as ester hydrolysis.
Codex Esterase Screening Kit
The Codex Esterase Screening Kit contains 12 esterase enzymes for amide synthesis or ester hydrolysis. This selected set of Esterase enzymes were developed using Codexis’ CodeEvolver® technology platform and have been engineered for enhanced activity, substrate range, and solvent and temperature stability. 100 g of each kit enzyme is available from stock, and larger quantities up to tons are available on demand. The kit contains 12 x 250 mg enzymes.
Ene Reductases perform the symmetric reduction of carbon-carbon double bonds in carbonyl conjugated alkene substrates using nicotinamide cofactors as electron donors.
Codex ERED Screening Kit
The Codex ERED Screening Kit contains 7 ene reductase enzymes for asymmetric C=C double bond reduction. This selected set of engineered enzymes has a broad substrate range, diverse stereoselectivity, improved solvent stability and can operate on a wide range of temperatures and pHs. 100 g of each kit enzyme is available from stock, and larger quantities up to tons are available on demand. The kit contains 7 x 250 mg EREDs, NADP+ cofactor, and a cofactor regeneration system.
Nitrilases are enzymes capable of hydrolyzing nitriles to carboxylic acids at neutral pH and ambient temperature.
Codex NIT Screening Kit
The Codex NIT Screening Kit contains 12 nitrilase enzymes for converting nitriles into carboxylic acids. This selected set of engineered enzymes has a broad substrate range, diverse stereoselectivity, improved solvent stability and can operate on a wide range of temperatures and pHs.100 g of each kit enzyme is available from stock, and larger quantities up to tons are available on demand. The kit contains 12 x 250 mg enzymes and a NIT reaction buffer mix.
MicroCyp P450 enzymes provide medicinal chemists and development scientists with unique tools to generate new molecules and metabolites. The Elite MicroCyp enzymes are improved over our Standard MicroCyp enzymes and have shown to be more active, have increased solvent tolerance and show greater substrate promiscuity. This makes them a valuable option where novel compounds or larger quantities of products are required.
MicroCyp Screening Kits
The Codex Standard MicroCyp Screening Kit contains 23 of our standard enzymes that are capable of producing mammalian-type metabolites and new compounds for lead diversification. Our MCYP enzymes are known to have up to 100-fold increased productivity when compared to Human CYP activity and hence, can be more cost effective when scaling reactions to produce gram quantities of your desired compound. 100 grams of each kit enzyme is available from stock for rapid delivery to our customers for scale-up work. The standard kit contains 23 enzymes arrayed in a 24-well plate, 1 screen per kit and 6 µM of P450 per well. Request a quote using the form below.
Our Elite MicroCyp enzymes are superior to our Standard MicroCyp® enzymes as they are more active, have increased solvent tolerance and show greater substrate promiscuity, which makes them a valuable option especially where novel compounds or larger quantities are required. The elite kit contains: 11 enzymes arrayed in duplicate wells in a 24-well plate, 2 screens per kit, and 6 µM of P450 per well. Request a quote using the form below.
Imine Reductases perform the asymmetric synthesis of secondary and tertiary chiral amines from imines, or ketones and amines.
Monoamine Oxidases convert amines to imines (asymmetric or resolution) using ambient oxygen as the oxidant.
Acylases are capable of ester formation/transesterification or ester hydrolysis.
Codexis’ engineered Baeyer-Villiger Monooxygenases perform the asymmetric oxidation of sulfide to sulfoxide using ambient oxygen as the oxidant, and with nicotinamide as a cofactor.
Halohydrin Dehalogenases perform nucleophilic displacement of halogen in a halohydrin.
Formate Dehydrogenase (FDH-101)
Formate Dehydrogenases enable the regeneration of NADH from NAD+ by catalyzing the oxidation of formate to bicarbonate. The driving force is the release of CO2. Our FDH-101 is a natural enzyme, with a specific activity of 4 U/mg.
Glucose Dehydrogenase (GDH-105 or 901)
Glucose dehydrogenase enables the regeneration of NAD(P)H from NAD(P)+ by catalyzing the oxidation of ß-D-glucose to D-glucono-1,5-lactone. Note that D-glucono-1,5-lactone is easily hydrolyzed to gluconic acid, thereby lowering the pH of the reaction. Codexis offers two different GDHs: GDH-105 and CDX-901 with a specific activity of ~50 U/mg. CDX-901 is our standard GDH and has been produced at MT scale, while GDH-105 is typically more thermo- and solvent stable.
Lactate Dehydrogenase (LDH-101)
L-Lactate dehydrogenase enables the regeneration of NAD+ from NADH by catalyzing the reduction of pyruvate to lactate. Our LDH-101 enzyme has a specific activity of ~60 U/mg.
Cofactors available
Platforms built for technical edge
Our proprietary platforms are precision-built to scale where traditional chemistry can’t.
ECO Synthesis® Manufacturing Platform
A modern, scalable RNA manufacturing platform that delivers quality, scalability, and sustainability.
CodeEvolver® Technology Platform
The engine powering scalable solutions others can’t replicate — powered by AI, machine learning, and deep enzymology expertise.
Talk to the Screening Kit Team
Have a target in mind? Let’s discuss the best kit for your chemistry.