Codex® HiCap RNA Polymerase at Codexis

Codex® HiCap RNA Polymerase

Codexis and Aldevron Enter Exclusive Licensing Agreement for Codex® HiCap RNA Polymerase

Deal creates strategic collaboration to enable more efficient RNA therapeutic development, providing a path to GMP-grade Codexis enzymes

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Improve mRNA capping efficiency

Achieve exceptional IVT results with Codex® HiCap RNA Polymerase, a co-transcriptional capping RNA polymerase that has been uniquely engineered to produce synthetic mRNA at high yield and low immunogenicity.

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Product benefits

More translatable mRNA with greater capping efficiency

Specifically designed to improve capping efficiency over current methods while reducing cap analog requirements, the Codex® HiCap RNA Polymerase increases yields of fully capped mRNA without compromising the total RNA yield.

Reduced immunogenicity from double-stranded RNA

Reduce the negative immune responses from your vaccine and therapeutic candidates with Codex® HiCap RNA Polymerase, which produces significantly less double-stranded RNA (dsRNA) compared to wild-type T7 RNA polymerase.

Flexible uracil analog incorporation

Codex® HiCap RNA Polymerase incorporates commonly used uracil analogs to replace canonical uracil (which can also elicit an unintended immune response) during IVT and is able to incorporate a range of commercial uracil analogs.

OEM enzyme supply

You can tailor Codex® HiCap RNA Polymerase purchase quantities, concentrations, and fill-volumes to meet your demands and integrate seamlessly into your IVT production process. To learn more, please contact us.

Codex® HiCap RNA Polymerase Distributors

Nacalai Tesque, Inc.
Phone: +81-75-211-2703
Address: 498 Higashitamaya-cho, Nijo Karasuma, Nakagyo-ku, Kyoto 604-0855

Inveniolife Technology Pvt. Ltd.
Contact: Rahul Shrivastava
Phone: +91 98938 62116
Address: Office No.118, Grow More Tower, Plot No.5, Sector 02, Kharghar, Navi Mumbai 410 210

FUJIFILM Wako Pure Chemical Corporation
Phone: +81-3-3270-8571
Address: 4-1 Nihonbashi Honcho 2-Chome, Chuo-Ku, Tokyo 103-0023, Japan

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