Codex® HiCap RNA Polymerase at Codexis

Codex® HiCap RNA Polymerase

Codexis and Aldevron Enter Exclusive Licensing Agreement for Codex® HiCap RNA Polymerase

Deal creates strategic collaboration to enable more efficient RNA therapeutic development, providing a path to GMP-grade Codexis enzymes

Learn More

Improve mRNA capping efficiency

Achieve exceptional IVT results with Codex® HiCap RNA Polymerase, a co-transcriptional capping RNA polymerase that has been uniquely engineered to produce synthetic mRNA at high yield and low immunogenicity.

Read data sheet

Product benefits

More translatable mRNA with greater capping efficiency

Specifically designed to improve capping efficiency over current methods while reducing cap analog requirements, the Codex® HiCap RNA Polymerase increases yields of fully capped mRNA without compromising the total RNA yield.

Reduced immunogenicity from double-stranded RNA

Reduce the negative immune responses from your vaccine and therapeutic candidates with Codex® HiCap RNA Polymerase, which produces significantly less double-stranded RNA (dsRNA) compared to wild-type T7 RNA polymerase.

Flexible uracil analog incorporation

Codex® HiCap RNA Polymerase incorporates commonly used uracil analogs to replace canonical uracil (which can also elicit an unintended immune response) during IVT and is able to incorporate a range of commercial uracil analogs.

OEM enzyme supply

You can tailor Codex® HiCap RNA Polymerase purchase quantities, concentrations, and fill-volumes to meet your demands and integrate seamlessly into your IVT production process. To learn more, please contact us.

Codex® HiCap RNA Polymerase Distributors

Japan
Nacalai Tesque, Inc.
Contact: reagent@nacalai.co.jp
Phone: +81-75-211-2703
Address: 498 Higashitamaya-cho, Nijo Karasuma, Nakagyo-ku, Kyoto 604-0855
Website: www.nacalai.co.jp

India
Inveniolife Technology Pvt. Ltd.
Contact: Rahul Shrivastava s.rahul@inveniolife.com
Phone: +91 98938 62116
Address: Office No.118, Grow More Tower, Plot No.5, Sector 02, Kharghar, Navi Mumbai 410 210

FUJIFILM Wako Pure Chemical Corporation
Contact: https://labchem-wako.fujifilm.com/jp/support/contact/index.html
Phone: +81-3-3270-8571
Address: 4-1 Nihonbashi Honcho 2-Chome, Chuo-Ku, Tokyo 103-0023, Japan
Website: https://labchem-wako.fujifilm.com

For more information, please contact us

There are many steps to a healthier future.

Join us on our journey.

Partner with us Join our team