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Unlocking the Future of RNA Manufacturing: A Guide to Enzymatic Synthesis

Unlock the Future of RNA Manufacturing

With Enzymatic Synthesis

Traditional solid-phase oligonuclueotide synthesis is struggling to keep pace with today’s increasing demands for RNA therapeutics. That’s why many developers are turning to enzyme-enabled RNA synthesis — a sustainable approach that’s designed to scale.

This ebook unpacks how this strategy is driving real results:

  • Cutting timelines with modular, parallel workflows
  • Supporting scalability beyond a 10 kg batch size
  • Improving yield while reducing environmental burden
  • Reducing purification of duplex RNA

These results are achieved using two key methods: ligation-based assembly of RNA fragments or fully sequential RNA synthesis.  See how leading drug developers are using these innovations to de-risk development and accelerating development time.

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