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Codex® HiFi Hot Start DNA Polymerase
Codex® HiFi Hot Start 2X NGS Mix available for OEM supply

Fully optimized and formulated for next-generation sequencing workflows, the Codex® HiFi Hot Start DNA Polymerase allows developers of NGS library preparation kits or diagnostic molecular assays to create kits that will give customers more confidence in their data, reducing the number of total reads required, even for low sample inputs, or at decreased depths of coverage.

Market-leading fidelity

With an approximately 400-fold increase in fidelity relative to Taq and greater than 2.5-fold improvement relative to the current market-leading, high-fidelity DNA polymerase, DNA libraries will be amplified with fewer errors, providing higher confidence in the data even at decreased depths over coverage.

Enhanced uniformity of coverage

Decreased GC bias increases library complexity and the number of unique reads. This means that fewer total reads are required to achieve a target mean depth of coverage, in turn providing higher confidence in the data with decreased coverage depth.

High yields

Including a proprietary aptamer to provide hot start specificity, libraries are amplified with high yields, critical for low sample inputs and workflows such as hybrid capture.

OEM enzyme supply

We can manufacture and fully formulate this enzyme to create a customized solution for you. To learn more, please contact us, or visit the Scale-up and Supply page.

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Looking for another engineered life science enzyme?

Sequencing & detection

Codexis’s novel enzymes are engineered to improve accuracy, speed, and overall robustness of your sequencing or diagnostic workflows such as NGS library preparation or RT-qPCR.

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