Leading Enzyme Science Since 2002
Codexis pioneered enzyme optimization for therapeutics and never stopped evolving. Our track record — from blockbuster APIs to next-gen RNA — shows what’s possible when science meets execution. For 20+ years, we’ve led with curiosity, precision, and proven results. We are committed to the continuation of innovation that’s always defined us. Because at Codexis, we’re not just part of the enzymatic revolution — we lead it.
Key Milestones
2025
ECO Innovation Lab Launched
Purpose-built R&D facility opens to advance the future of enzymatic oligonucleotide manufacturing.
2023–2025
RNA and Diagnostic Expansion
Built out RNA ligation platform and bespoke enzyme innovation for molecular biology and diagnostic applications.
2022
RNA Therapeutics Program Launched
Formal entry into RNA manufacturing — enzymatic synthesis, ligation, and custom enzyme solutions.
2021
Paxlovid Emergency Response
Scaled production of engineered enzyme for Pfizer’s COVID-19 antiviral in record time (30MT scale).
2012
Major Pharma Collaborations Begin
Codexis enzymes power synthesis of sitagliptin (Januvia®) with Merck.
2010
IPO on NASDAQ
Codexis becomes a public company (CDXS), expanding reach and investment.
2006
Strategic Focus Shift
Began pivoting toward biopharma with new R&D direction.
2002
Codexis Founded
Born as a platform company focused on industrial enzyme applications.
Here For Your Journey
Our R&D and GMP manufacturing sites are both based in Northern California, just eight miles apart. This proximity means greater agility, speed, and alignment from innovation to scale-up — providing the infrastructure that supports our partners’ evolving needs across RNA, small molecules, and diagnostic applications.
Unlock Therapeutic Possibilities at Scale
RNA manufacturing
Evolve beyond traditional chemistry with a modern and efficient approach that slots seamlessly into your existing process. Our enzyme-enabled RNA manufacturing platform delivers superior quality, higher yield, better manufacturability and faster results — through a greener solution. A future you can believe in, sooner than you thought possible.
Pharma biocatalysis
Transform complex, resource-intensive processes into precise, efficient and sustainable breakthroughs. Our proprietary enzymes — powered by CodeEvolver® Technology Platform — enable greener processes, faster pathways and world-class quality from grams to tonnes. Unlock new possibilities with pharma biocatalysisand elevate your process with sustainable chemistry designed to optimize API synthesis.
Molecular biology and diagnostic applications
Codexis redefines enzyme performance for molecular biology and diagnostic applications. Our CodeEvolver® platform enables tailored enzyme solutions with improved fidelity, enhanced selectivity, and increased activity, delivering faster reaction times to power your applications. As your trusted partner for enzyme evolution, we deliver precision-optimized solutions that power performance.
Platforms built for technical edge
Our proprietary platforms are precision-built to scale where traditional chemistry can’t.
ECO Synthesis® Manufacturing Platform
A modern, scalable RNA manufacturing platform that delivers quality, scalability, and sustainability.
CodeEvolver® Technology Platform
The engine powering scalable solutions others can’t replicate — powered by AI, machine learning, and deep enzymology expertise.
Let's Pave Your Path to the Future
Want to discuss our platform, pipeline, or partnership potential?