Exhibit 12.1

CODEXIS, INC.

STATEMENT OF COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

(In Thousands)
 

 
 
 
 
Years Ended December 31,
 
 
 
 
2013
 
 
2014
 
2015
 
2016
 
2017
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Fixed charges:
 
 
 
 
 
 
 
 
 
 
 
 
 
Interest Expense
 
$
13

 
 
$
—


 
 
$
—


 
 
$
14

 
 
$
141
 
 
Total Fixed Charges
 
 
13


 
 
—
 

 
 
—
 

 
 
14

 
 
141

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Earnings (deficiency) available for fixed charges:
 
 
 
 
 
 
 
 
 
 
 
 
 
Pre-tax income(loss) from continuing operations
 
 
(41,390)

 
 
(19,327)
 
 
 
(7,919)
 
 
 
(8,598)
 
 
(23,239)
 
 
add: Fixed Charges
 
 
13


 
 
—
 

 
 
—
 

 
 
14

 
 
141

 
 
Earnings(deficiency of earnings) available to cover fixed charges
 
$
(41,377)

 
 
$
(19,327)

 
 
$
(7,919)

 
 
$
(8,584)
 
 
$
(23,098)
 
Ratio of earnings to fixed charges (1)
 
 
 N/A

 
 
 N/A
 
 N/A
 
 N/A
 
 N/A

 
 
 
 
(1)
Our earnings were inadequate to cover fixed charges for the years ended December 31, 2013 through December 31, 2017.