Exhibit 12.1

CODEXIS, INC.

STATEMENT OF COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

(In Thousands)
 

 
 
 
 
Years Ended December 31,
 
 
 
 
2012
 
2013
 
2014
 
2015
 
2016
 
 
 
 
 
 
 
 
 
 
 
 
 
Fixed charges:
 
 
 
 
 
 
 
 
 
 
 
Interest Expense
 
$
—

 
$
13

 
$
—

 
$
—

 
$
14

 
 
Total Fixed Charges
 
—

 
13

 
—

 
—

 
14

 
 
 
 
 
 
 
 
 
 
 
 
 
Earnings (deficiency) available for fixed charges:
 
 
 
 
 
 
 
 
 
 
 
Pre-tax income(loss) from continuing operations
 
(30,587
)
 
(41,390
)
 
(19,327
)
 
(7,919
)
 
(8,598
)
 
add: Fixed Charges
 
—

 
13

 
—

 
—

 
14

 
 
Earnings(deficiency of earnings) available to cover fixed charges
 
$
(30,587
)
 
$
(41,377
)
 
$
(19,327
)
 
$
(7,919
)
 
$
(8,584
)
Ratio of earnings to fixed charges (1)
 
 N/A
 
 N/A
 
 N/A
 
 N/A
 
 N/A

 
(1)
Our earnings were inadequate to cover fixed charges for the years ended December 31, 2012 through December 31, 2016.