The power and possibilities of engineered proteins
Scientific Showcase
Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction
Codexis Authors: Dr. Fabien L. Cabirol, Dr. Haibin Chen, Anupam P. Gohel, Dr. Steven J. Collier, Dr. Derek J. Smith, Dr. Oscar Alvizo All Authors: Dr. Feng Xu, Dr. Birgit Kosjek, Richard...
May 16, 2018
Early Biotherapeutic Lead Optimization for More Efficient Drug Discovery and Development
Author: Gjalt Huisman, Vice President and Head of Biotherapeutics Summary Lead optimization for discovery of small molecule drug candidates is well established, but less so for biological drug...
May 8, 2018
Riding the Wave of the Protein Revolution: Optimized Biocatalysts for the Pharmaceutical and Food Industries
Authors: Dipnath Baidyaroy, Director, Strategic Alliances, Business Operations Stefanie Ng Minor, Manager, Product Management, Business Operations Revolutionary advances in digital technology,...
May 1, 2018
Improving ERTs with CodeEvolver Protein Engineering Technology to Improve Protein Stability and in vivo Half-Life, as Well as Reduce Immune Response
Authors: Kristen Skvorak, Nick Agard, Chinping Chng, Nikki Dellas, William Hallows, Matt Miller, Jinsong Shen, Judy Viduya, Xiyun Zhang, Cynthia Zhu, Raphael Schiffmann, and Gjalt Huisman Inborn...
March 29, 2018
An Engineered DNA Ligase for Efficient Conversion of Input DNA During NGS Library Preparation
Authors: Matt Miller, Scott Baskerville, Nikki Dellas, David Elgart, Sandy Gomes, Vesna Mitchell, Jonathan Penfield, Judy Viduya, and Jonathan Vroom Next-generation sequencing technologies have...
March 29, 2018
Adding Value in Pharma: Applying Advanced Protein Engineering Technologies to Biotherapeutic Development
Author: Gjalt Huisman, Ph.D., VP Pharmaceutical Technology & Innovation By applying its CodeEvolver® directed evolution technology, Codexis has been improving enzymes for specific functions...
November 20, 2017Biocatalysis for APIs: Engineered Enzymes Pave Easier, Faster Road to Scalable API Manufacturing
Author: Michael Aldridge, Senior Vice President, Corporate & Strategic Development Even the most promising and innovative API is going to be of little value unless it can be affordably...
November 9, 2017
Accelerating Drug Development and Manufacturing with Engineered Enzymes
Author: Rob Wilson, Ph.D., Sr. Director, Business Operations In 2016, the (bio)pharmaceutical industry continues to face escalating demands to improve productivity, build pipelines faster,...
April 4, 2016
Origins of Stereoselectivity in Evolved Ketoreductases
Codexis Authors: Jack Liang, Xiyun Zhang, Gjalt W. Huisman All Authors: Elizabeth L. Noey, Nidhi Tibrewal, Gonzalo Jiménez-Osés , Sílvia Osuna, Jiyong Park, Carly M. Bond, Duilio Cascio, Jack...
December 8, 2015
Harnessing the Power of P450 Enzymes for Large-Scale Manufacturing
Author: Robert Osborne, Ph.D., Scientist II Technical Lead Cytochrome P450 monooxygenases (P450s) have been the subject of extensive research for decades. These enzymes are involved in numerous...
February 4, 2015Since 2002, Codexis has created new technologies to unlock the power of proteins™. Put our unmatched protein engineering expertise to work for you.
Unlock the power of proteins™ with Codexis
Learn More
Company
Industries