The power and possibilities of engineered proteins
Scientific Showcase
Improving ERTs with CodeEvolver Protein Engineering Technology to Improve Protein Stability and in vivo Half-Life, as Well as Reduce Immune Response
Authors: Kristen Skvorak, Nick Agard, Chinping Chng, Nikki Dellas, William Hallows, Matt Miller, Jinsong Shen, Judy Viduya, Xiyun Zhang, Cynthia Zhu, Raphael Schiffmann, and Gjalt Huisman Inborn...
March 29, 2018
An Engineered DNA Ligase for Efficient Conversion of Input DNA During NGS Library Preparation
Authors: Matt Miller, Scott Baskerville, Nikki Dellas, David Elgart, Sandy Gomes, Vesna Mitchell, Jonathan Penfield, Judy Viduya, and Jonathan Vroom Next-generation sequencing technologies have...
March 29, 2018
Adding Value in Pharma: Applying Advanced Protein Engineering Technologies to Biotherapeutic Development
Author: Gjalt Huisman, Ph.D., VP Pharmaceutical Technology & Innovation By applying its CodeEvolver® directed evolution technology, Codexis has been improving enzymes for specific functions...
November 20, 2017Biocatalysis for APIs: Engineered Enzymes Pave Easier, Faster Road to Scalable API Manufacturing
Author: Michael Aldridge, Senior Vice President, Corporate & Strategic Development Even the most promising and innovative API is going to be of little value unless it can be affordably...
November 9, 2017
Accelerating Drug Development and Manufacturing with Engineered Enzymes
Author: Rob Wilson, Ph.D., Sr. Director, Business Operations In 2016, the (bio)pharmaceutical industry continues to face escalating demands to improve productivity, build pipelines faster,...
April 4, 2016
Origins of Stereoselectivity in Evolved Ketoreductases
Codexis Authors: Jack Liang, Xiyun Zhang, Gjalt W. Huisman All Authors: Elizabeth L. Noey, Nidhi Tibrewal, Gonzalo Jiménez-Osés , Sílvia Osuna, Jiyong Park, Carly M. Bond, Duilio Cascio, Jack...
December 8, 2015
Harnessing the Power of P450 Enzymes for Large-Scale Manufacturing
Author: Robert Osborne, Ph.D., Scientist II Technical Lead Cytochrome P450 monooxygenases (P450s) have been the subject of extensive research for decades. These enzymes are involved in numerous...
February 4, 2015
Directed Evolution of an Ultrastable Carbonic Anhydrase for Highly Efficient Carbon Capture From Flue Gas
Carbonic anhydrase (CA) is one of nature’s fastest enzymes and can dramatically improve the economics of carbon capture under demanding environments such as coal-fired power plants. The use of CA...
November 4, 2014Since 2002, Codexis has created new technologies to unlock the power of proteins™. Put our unmatched protein engineering expertise to work for you.
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