The power and possibilities of engineered proteins
Scientific Showcase
Baeyer–Villiger Monooxygenase-Mediated Synthesis of Esomeprazole As an Alternative for Kagan Sulfoxidation
Codexis Authors: Yong Koy Bong, Shiwei Song, Jovana Nazor, Michael Vogel, Magnus Widegren, Derek Smith, Steven J. Collier, Rob Wilson, S. M. Palanivel, Karthik Narayanaswamy, Ben Mijts, Michael...
August 15, 2018
Panel Discussion on Catalysis or Biocatalysis?
Codexis Author: Jim Lalonde, Ph.D., Senior Vice President of Research & Development All Authors: Beatriz Dominguez, Jürgen Rotzler, Christophe Le Ret, Stéphane Corgié Abstract: The panel...
June 28, 2018
Green Techniques for Organic Synthesis and Medicinal Chemistry, 2nd Edition
Codexis Author: Jim Lalonde, Ph.D., Senior Vice President of Research & Development Edited by: Wei Zhang and Berkeley W. Cue Abstract: This definitive, essential 728-page textbook on the...
June 27, 2018
Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction
Codexis Authors: Dr. Fabien L. Cabirol, Dr. Haibin Chen, Anupam P. Gohel, Dr. Steven J. Collier, Dr. Derek J. Smith, Dr. Oscar Alvizo All Authors: Dr. Feng Xu, Dr. Birgit Kosjek, Richard...
May 16, 2018
Early Biotherapeutic Lead Optimization for More Efficient Drug Discovery and Development
Author: Gjalt Huisman, Vice President and Head of Biotherapeutics Summary Lead optimization for discovery of small molecule drug candidates is well established, but less so for biological drug...
May 8, 2018
Riding the Wave of the Protein Revolution: Optimized Biocatalysts for the Pharmaceutical and Food Industries
Authors: Dipnath Baidyaroy, Director, Strategic Alliances, Business Operations Stefanie Ng Minor, Manager, Product Management, Business Operations Revolutionary advances in digital technology,...
May 1, 2018
Improving ERTs with CodeEvolver Protein Engineering Technology to Improve Protein Stability and in vivo Half-Life, as Well as Reduce Immune Response
Authors: Kristen Skvorak, Nick Agard, Chinping Chng, Nikki Dellas, William Hallows, Matt Miller, Jinsong Shen, Judy Viduya, Xiyun Zhang, Cynthia Zhu, Raphael Schiffmann, and Gjalt Huisman Inborn...
March 29, 2018
An Engineered DNA Ligase for Efficient Conversion of Input DNA During NGS Library Preparation
Authors: Matt Miller, Scott Baskerville, Nikki Dellas, David Elgart, Sandy Gomes, Vesna Mitchell, Jonathan Penfield, Judy Viduya, and Jonathan Vroom Next-generation sequencing technologies have...
March 29, 2018
Adding Value in Pharma: Applying Advanced Protein Engineering Technologies to Biotherapeutic Development
Author: Gjalt Huisman, Ph.D., VP Pharmaceutical Technology & Innovation By applying its CodeEvolver® directed evolution technology, Codexis has been improving enzymes for specific functions...
November 20, 2017Biocatalysis for APIs: Engineered Enzymes Pave Easier, Faster Road to Scalable API Manufacturing
Author: Michael Aldridge, Senior Vice President, Corporate & Strategic Development Even the most promising and innovative API is going to be of little value unless it can be affordably...
November 9, 2017Since 2002, Codexis has created new technologies to unlock the power of proteins™. Put our unmatched protein engineering expertise to work for you.
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