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February 19, 2013

Strem and Codexis Sign Enzyme Distribution Agreement

NEWBURYPORT, Mass. & REDWOOD CITY, Calif.–(BUSINESS WIRE)–Feb. 19, 2013–
Strem Chemicals, Inc., a manufacturer of specialty chemicals for
research and development and Codexis, Inc. (NASDAQ: CDXS), a developer
of world-leading enzymes and processes for the production of
pharmaceuticals, biofuels and bio-based chemicals, today announced the
signing of an enzyme distribution agreement.

The agreement grants Strem exclusive distribution rights for the new
100mg CODEX® Screening Kits for Codexis’ popular Transaminase
and Ketoreductase enzyme platforms. These enzymes enable efficient
conversion of ketones to chiral alcohols or amines.

The screening kits contain enzymes evolved with proprietary CodeEvolver®
directed evolution technology. The resulting enzymes are designed to
work at industrial process conditions while reducing cost and waste.
They will be available through Strem’s overnight delivery service so
that researchers are able to quickly screen a small number of diverse
biocatalysts to pick the best solution.

“We are pleased to announce this partnership with Strem, a company very
well established in the distribution of catalysts to a wide customer
base,” said Dr. Peter Seufer-Wasserthal, Senior Vice President,
Pharmaceuticals at Codexis. “Based on Strem’s proven network, we are
looking forward to giving more customers the opportunity to use
industrial enzymes at R&D scale.”

“Strem is pleased to be working with a proven market leader in the field
of Biocatalysis,” said Ephraim Honig, Chief Operating Officer at Strem.
“The addition of these screening kits broadens the range of synthesis
tools we offer our customers and acknowledges the increasingly important
role this technology plays in drug discovery and development.”

About Strem Chemicals

Strem Chemicals, Inc., established in 1964, is a privately held
manufacturer and marketer of specialty chemicals of high purity. Strem’s
key products include catalysts, ligands, organometallics, metal
carbonyls and nanomaterials. Its products are used for research and
development and commercial scale applications, especially in the
pharmaceutical, microelectronics, chemicals and petrochemicals
industries. Strem Chemicals also provides custom synthesis, process
development and cGMP manufacturing services. For more information visit www.strem.com.

About Codexis, Inc.

Codexis, Inc. is a developer of world-leading enzymes and processes for
the production of pharmaceuticals, biofuels and bio-based chemicals.
Codexis’ product lines include CodeXyme™ cellulase enzymes and CodeXol™
detergent alcohol. Partners and customers include global leaders such as
Merck, Pfizer and Arch Pharmalabs. For more information, see www.codexis.com.

Source: Codexis, Inc.

Strem Chemicals, Inc.
Media: press@strem.com
or
Codexis,
Inc.
Investors:
Paul Cox, 212-362-1200
ir@codexis.com
Media:
media@codexis.com

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