Technical Papers
- Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture
Science, June 17, 2010
— Abstract
— Reprint - Development of a Biocatalytic Process as an Alternative to the (-)-DIP-Cl-Mediated Asymmetric Reduction of a Key Intermediate of Montelukast
Organic Process Research & Development, 2010, Vol 14 - Practical chiral alcohol manufacture using ketoreductases
Current Opinion in Chemical Biology, 2009, 14 - Enzyme optimization: moving from blind evolution to statistical exploration
of sequence-function space
Trends in Biotechnology; March 2008. - Biocatalysis: Giving Nature a Helping Hand
sp2; August 2007. - Improving catalytic function by ProSAR-driven enzyme evolution
Nature Biotechnology; March 7, 2007.
